disease has basis in dysfunction of disease caused by disruption of disease has basis in disruption of GLA alpha-galactosidase activity congenital nervous system disorder Fabry disease Alpha-galactosidase A deficiency Anderson-Fabry disease DOID:14499 Fabry disease Fabry disease (FD) is a progressive, inherited, multisystemic lysosomal storage disease characterized by specific neurological, cutaneous, renal, cardiovascular, cochleo-vestibular and cerebrovascular manifestations. Fabry disease, Cardiac variant Fabry's disease Fd GARD:0006400 Gla deficiency ICD10:E75.2 ICD10:E75.21 MESH:D000795 MONDO:0010526 MedDRA:10016016 NCIT:C84701 OMIM:301500 Orphanet:324 SCTID:16652001 UMLS:C0002986 alpha galactosidase deficiency angiokeratoma corporis diffusum angiokeratoma, diffuse ceramide trihexosidase deficiency deficiency of melibiase diffuse angiokeratoma hereditary dystopic lipidosis developmental anomaly of metabolic origin syndromic dyslipidemia rare hereditary metabolic disease with peripheral neuropathy lysosomal disease with hypertrophic cardiomyopathy lysosomal disease with restrictive cardiomyopathy lysosomal disease with epilepsy sphingolipidosis skin vascular disease hereditary lymphedema syndromic lymphedema nephropathy secondary to a storage or other metabolic disease cataract associated with a metabolic disease metabolic disease with corneal opacity genetic skin disease neurovascular disease disease of catalytic activity