disease has basis in dysfunction of UMOD autosomal dominant medullary cystic kidney disease with or without hyperuricemia medullary cystic kidney disease 2 An inherited form of cystic kidney disease leading to fibrosis and impaired renal function that is caused by mutations in the UMOD gene, which encodes uromodulin/Tamm-Horsfall mucoprotein. EFO:0008618 MCKD2 MONDO:0011379 NCIT:C123172 OMIM:603860 SCTID:445503007 UMLS:C4054550 medullary cystic kidney disease 2 medullary cystic kidney disease 2, autosomal dominant medullary cystic kidney disease type 2 medullary cystic kidney disease type II