disease has basis in dysfunction of GLIS3 neonatal diabetes mellitus with congenital hypothyroidism A rare genetic disease characterized by intrauterine growth retardation, permanent neonatal diabetes mellitus, and congenital hypothyroidism. Additional manifestations include congenital glaucoma, hepatic disease (hepatitis, fibrosis, and cirrhosis), polycystic kidneys, exocrine pancreatic dysfunction, sensorineural hearing impairment, developmental delay, and mild facial dysmorphism (such as flat nasal bridge, epicanthal folds, long philtrum, and low-set ears), among others DOID:0060638 MESH:C565705 MONDO:0012436 NDH NDH syndrome Ndh syndrome OMIM:610199 Orphanet:79118 UMLS:C1857775 diabetes mellitus, neonatal, with congenital hypothyroidism neonatal diabetes-congenital hypothyroidism-congenital glaucoma-hepatic fibrosis-polycystic kidneys syndrome neonatal diabetes mellitus inborn errors of metabolism familial cystic renal disease