disease has basis in dysfunction of FGFR3 autosomal dominant disease focal segmental glomerulosclerosis Crouzon syndrome-acanthosis nigricans syndrome CAN Chronic kidney allograft nephropathy Crouzon syndrome with acanthosis nigricans Crouzon syndrome with acanthosis nigricans (CAN) is a very rare, clinically heterogeneous form of faciocraniostenosis with Crouzon-like features and premature synostosis of cranial sutures (Crouzon disease), associated with acanthosis nigricans (AN). Crouzon-dermoskeletal syndrome Crouzonodermoskeletal syndrome DOID:0111161 ICD10:Q75.1 MESH:C567382 MONDO:0012833 NCIT:C38145 OMIM:612247 Orphanet:93262 SCTID:702361006 can chronic allograft nephropathy syndromic craniosynostosis syndrome with a symptomatic strabismus