disease has basis in dysfunction of GNAS pseudohypoparathyroidism type 1C GARD:0010681 ICD10:E20.1 MESH:C548076 MONDO:0012911 OMIM:612462 Orphanet:79444 PHP1C Php 1C Pseudohypoparathyroidism type 1c (PHP1c) is a rare type of pseudohypoparathyroidism (PHP) characterized by resistance to parathyroid hormone (PTH) and other hormones, which manifests with hypocalcemia, hyperphosphatemia and elevated PTH levels, a constellation of clinical features collectively termed Albright's hereditary osteodystrophy (AHO), but normal activity of the stimulatory protein G (Gs alpha). SCTID:717792007 UMLS:C2932716 https://rarediseases.info.nih.gov/diseases/10681/pseudohypoparathyroidism-type-1c pseudohypoparathyroidism, type 1C pseudohypoparathyroidism, type IC syndromic genetic obesity primary avascular necrosis avascular necrosis of genetic origin other genetic dermis disorder acromelic dysplasia pseudohypoparathyroidism musculoskeletal disease with cataract dermis disease genetic skin disease