disease has basis in dysfunction of REN familial juvenile hyperuricemic nephropathy familial juvenile hyperuricemic nephropathy type 2 ADTKD-REN FJHN type 2 Familial juvenile hyperuricemic nephropathy type 2 is a rare autosomal dominantly inherited disease of childhood characterized by hypoproliferative anemia, hyperuricemia and slowly progressing kidney failure due to dysregulation of the renin-angiotensin system (RAS). HNFJ2 MESH:C567760 MONDO:0013128 OMIM:613092 Orphanet:217330 REN familial juvenile hyperuricemic nephropathy REN-associated FJHN REN-associated familial juvenile hyperuricemic nephropathy REN-associated kidney disease REN-related autosomal dominant tubulointerstitial kidney disease SCTID:721840000 autosomal dominant tubulointerstitial kidney disease due to mutations in REN early-onset hyperuricemia, Anemia, and progressive kidney failure familial juvenile hyperuricemic nephropathy caused by mutation in REN familial juvenile hyperuricemic nephropathy type 2 hyperuricemic nephropathy, familial juvenile, 2 hyperuricemic nephropathy, familial juvenile, type 2 inherited renal tubular disease rare renal tubular disease