disease has basis in dysfunction of SERPINA1 syndromic disease plasma protein metabolism disease respiratory system disease alpha 1-antitrypsin deficiency A-1ATD A1AD A1AT deficiency A1ATD AAT deficiency AATD ALPHA-1-antitrypsin deficiency Alpha 1 antitrypsin deficiency Alpha-1 antitrypsin deficiency Alpha-1-antitrypsin deficiency is a hereditary disease that develops in adulthood and is characterized by chronic liver disorders (cirrhosis), respiratory disorders (emphysema), and rarely panniculitis. COHD:192275 DOID:13372 GARD:0005784 ICD10:E88.0 ICD10:E88.01 ICD9:273.4 MESH:D019896 MONDO:0013282 MedDRA:10001806 NCIT:C84397 OMIM:613490 Orphanet:60 SCTID:30188007 UMLS:C0221757 alpha-1-antitrypsin deficiency deficiency in Alpa-1-proteinase inhibitor https://rarediseases.info.nih.gov/diseases/5784/alpha-1-antitrypsin-deficiency other inborn metabolic disease nephropathy secondary to a storage or other metabolic disease