cystic kidney disease medullary sponge kidney COHD:195072 Cacchi Ricci disease Cacchi-Ricci disease Cacchi-Ricci syndrome GARD:0000232 ICD10:Q61.5 ICD9:753.17 MESH:D007691 MONDO:0015268 MSK MedDRA:10027104 Medullary sponge kidney (MSK) is a birth defect of the tubules - tiny tubes inside the kidneys. In a normal kidney, urine flows through these tubules as it is being formed. In MSK, tiny sacs called cysts form in the medulla (the inner part of the kidney), creating a sponge-like appearance. The cysts keep urine from flowing freely through the tubules. MSK is present at birth but symptoms typically do not occur until adolescence or adulthood. Problems caused by MSK include blood in the urine, kidney stones, and urinary tract infections. MSK rarely leads to more serious problems, such as total kidney failure. There is no cure for this condition, so treatment is aimed at removing kidney stones and treating urinary tract infections with antibiotics. NCIT:C34751 Orphanet:1309 Precalicial canalicular ectasia Precalyceal canalicular ectasia SCTID:236443009 UMLS:C0022681 cystic dilatation of renal collecting tubes https://rarediseases.info.nih.gov/diseases/232/medullary-sponge-kidney sponge kidney non-syndromic renal or urinary tract malformation