disease caused by disruption of disease has basis in disruption of glycosylation congenital disorder of glycosylation CDG Congenital disorder of glycosylation (CDG) is a fast growing group of inborn errors of metabolism characterized by defective activity of enzymes that participate in glycosylation (modification of proteins and other macromolecules by adding and processing of oligosaccharide side chains). CDG is comprised of phenotypically diverse disorders affecting multiple systems including the central nervous system, muscle function, immunity, endocrine system, and coagulation. The numerous entities in this group are subdivided, based on the synthetic pathway affected, into disorder of protein N-glycosylation, disorder of protein O-glycosylation, disorder of multiple glycosylation, and disorder of glycosphingolipid and glycosylphosphatidylinositol anchor glycosylation. DOID:5212 GARD:0010307 ICD10:E77.8 ICD9:271.8 MESH:D018981 MONDO:0015286 NCIT:C84615 OMIMPS:212065 Orphanet:137 SCTID:238049009 UMLS:C0282577 carbohydrate deficient glycoprotein syndrome carbohydrate-deficient glycoprotein syndrome carbohydrate-deficient glycoprotein syndromes congenital disorders of glycosylation inborn errors of metabolism inborn carbohydrate metabolic disorder disorder of glycosylation