Charcot-Marie-Tooth disease An inherited degenerative disorder involving the peripheral nerves. It is caused by mutations in the genes that are responsible for the production of proteins necessary for the function and structure of the peripheral nerves. It is characterized by muscle atrophy and weakness in the feet, legs, hands, and arms and loss of sensation in the limbs. CMT CMT - Charcot-Marie-Tooth disease CMT/HMSN Charcot Marie Tooth disease Charcot Marie Tooth muscular atrophy Charcot-Marie-Tooth disease Charcot-Marie-Tooth disease/hereditary motor and sensory neuropathy Charcot-Marie-Tooth hereditary neuropathy DOID:10595 GARD:0006034 ICD10:G60.0 ICD9:356.1 MESH:D002607 MONDO:0015626 MedDRA:10034699 NCIT:C75467 OMIMPS:118220 Orphanet:166 UMLS:C0007959 hereditary motor and sensory neuropathy hereditary sensorimotor neuropathy peroneal muscular atrophy neuromuscular disease genetic peripheral neuropathy