distal renal tubular acidosis (disease) Distal renal tubular acidosis (dRTA) is a disorder of impaired net acid secretion by the distal tubule characterized by hyperchloremic metabolic acidosis. The classic form is often associated with hypokalemia whereas other forms of acquired dRTA may be associated with hypokalemia, hyperkalemia or normokalemia. GARD:0004667 HP:0008341 ICD10:N25.8 ICD9:588.89 MONDO:0015827 MedDRA:10045224 OMIMPS:179800 Orphanet:18 SCTID:236461000 classic RTA dRTA distal renal tubular acidosis familial distal primary acidosis renal tubular acidosis type 1 renal tubular acidosis, distal primary renal tubular acidosis