cryopyrin-associated periodic syndrome Cryopyrin associated periodic syndrome (CAPS) defines a group of autoinflammatory diseases, characterized by recurrent episodes of systemic inflammatory attacks in the absence of infection or autoimmune disease. CAPS comprises 3 disorders on a continuum of severity: severe CINCA syndrome, intermediate Muckle-Wells syndrome (MWS) and milder familial cold urticaria (FCAS). Cryopyrinopathy GARD:0010927 ICD10:E85.0 ICD9:759.89 MESH:D056587 MONDO:0016168 MedDRA:10068850 NCIT:C84657 Orphanet:208650 SCTID:430079001 UMLS:C2316212 caps autoinflammatory syndrome with immune deficiency autoinflammatory syndrome with skin involvement hereditary periodic fever syndrome