disease disrupts disease causes disruption of disease has location lysosome cysteine homeostasis cystinosis Cystinoses Cystinosis is a metabolic disease characterized by an accumulation of cystine inside the lysosomes, causing damage in different organs and tissues, particularly in the kidneys and eyes. Three clinical forms have been described: nephropathic infantile, nephropathic juvenile and ocular. DOID:1064 GARD:0006236 ICD10:E72.0 ICD10:E72.04 MESH:D003554 MONDO:0016239 MedDRA:10011777 NCIT:C2976 Orphanet:213 Protein defect of cystin transport SCTID:190681003 UMLS:C0010690 UMLS:CN035091 cystine diathesis cystine disease cystine storage disease https://rarediseases.info.nih.gov/diseases/6236/cystinosis inborn disorder of lysosomal amino acid transport