congenital hydrocephalus hydrocephalus-blue sclerae-nephropathy syndrome Daentl-Townsend-Siegel syndrome Hydrocephalus-blue sclera-nephropathy syndrome is a rare, genetic, renal or urinary tract malformation syndrome characterized by nephrotic syndrome with focal segmental sclerosis associated with hydrocephalus, thin skin and blue sclerae. There have been no further descriptions in the literature since 1978. ICD10:Q87.8 MONDO:0016350 Orphanet:2186 syndromic renal or urinary tract malformation