systemic sclerosis diffuse cutaneous systemic sclerosis DcSSc Diffuse cutaneous systemic sclerosis (dcSSc) is a subtype of Systemic Sclerosis (SSc) characterized by truncal and acral skin fibrosis with an early and significant incidence of diffuse involvement (interstitial lung disease, oliguric renal failure, diffuse gastrointestinal disease, and myocardial involvement). GARD:0009751 ICD10:M34.0 MONDO:0016356 NCIT:C116791 Orphanet:220393 dSSc diffuse cutaneous systemic scleroderma https://rarediseases.info.nih.gov/diseases/9751/diffuse-cutaneous-systemic-sclerosis progressive cutaneous systemic scleroderma progressive cutaneous systemic sclerosis