has modifier hyperaldosteronism Mendelian disease rare non surgically correctable form of primary aldosteronism familial hyperaldosteronism FH Familial hyperaldosteronism (FH) is the heritable form of primary aldosteronism (PA) which comprises three identified subtypes to date: FH type I (FH-I) characterized by early-onset hypertension, glucocorticoid remediable adrenocorticotropic hormone (ACTH)-dependent hyperaldosteronism, variable hypokalemia, and overproduction of 18-oxocortisol and 18-hydroxycortisol; FH type II (FH-II) characterized by hypertension of varying severity and hyperaldosteronism not suppressible by dexamethasone; and FH type III (FH-III) characterized by profound hypokalemia, early-onset severe hypertension, non glucocorticoid-remediable hyperaldosteronism, and overproduction of 18-oxocortisol and 18-hydroxycortisol. ICD10:E26.0 MESH:C580087 MONDO:0016525 NCIT:C127160 OMIMPS:103900 Orphanet:235936 Orphanet:371861 SCTID:703231005 UMLS:C3713420 UMLS:CN229602 genetic hyperaldosteronism hereditary hyperaldosteronism inherited