renal tubular dysgenesis GARD:0000379 ICD10:Q63.8 MONDO:0017609 Orphanet:3033 Renal tubular dysgenesis is a rare disorder of the fetus characterized by absent or poorly developed proximal tubules of the kidneys, persistent oligohydramnios, leading to Potter sequence (facial dysmorphism with large and flat low-set ears, lung hypoplasia arthrogryposis and limb positioning defects), and skull ossification defects. It can be acquired during fetal development due to drugs taken by the mother or certain disorders (twin-twin transfusion syndrome, TTTS) or inherited in an autosomal recessive manner. SCTID:702397002 primitive renal tubule syndrome renotubular dysgenesis non-syndromic renal or urinary tract malformation