has modifier Autosomal dominant inheritance autosomal dominant disease proximal renal tubular acidosis autosomal dominant proximal renal tubular acidosis AD pRTA Autosomal dominant proximal renal tubular acidosis (AD pRTA) is a form of proximal renal tubular acidosis (pRTA) characterized by an isolated defect in the proximal tubule leading to the decreased reabsorption of bicarbonate and consequently causing urinary bicarbonate wastage. Mild growth retardation and reduced bone density are extra-renal complications. ICD10:N25.8 MONDO:0017829 Orphanet:314889 UMLS:CN203801 proximal renal tubular acidosis, autosomal dominant