has modifier disease has inflammation site disease or disorder vascular disease vasculitis DOID:865 EFO:0006803 GARD:0009565 MESH:D014657 MONDO:0018882 MedDRA:10036023 MedDRA:10047115 NCIT:C26912 Orphanet:52759 SCTID:31996006 UMLS:C0042384 Vasculitis represents a clinically heterogenous group of diseases of multifactorial etiology characterized by inflammation of either large-sized vessels (large-vessel vasculitis, e.g. Giant-cell arteritis and Takayasu arteritis), medium-sized vessels (medium-vessel vasculitis e.g. polyarteritis nodosa and Kawasaki disease), or small-sized vessels (small-vessel vasculitis, e.g. granulomatosis with polyangiitis, microscopic polyangiitis, immunoglobulin A vasculitis, and cutaneous leukocytoclastic angiitis). Vasculitis occurs at any age, may be acute or chronic, and manifests with general symptoms such as fever, weight loss and fatigue, as well as more specific clinical signs depending on the type of vessels and organs affected. The degree of severity is variable, ranging from life or sight threatening disease (e.g. BehC'et disease) to relatively minor skin disease. Wikipedia:Vasculitis angiitis systemic vasculitis systemic or rheumatic disease rare inflammatory disease vasculature