glomerulonephritis (disease) primary glomerular disease primary membranoproliferative glomerulonephritis COHD:433257 GARD:0011982 ICD10:N00.5 ICD9:583.2 MONDO:0018904 MPGN MedDRA:10018370 Membranoproliferative glomerulonephritis (MPGN) is a chronic progressive kidney disorder characterized by glomerular capillary wall structural changes and mesangial cell proliferation leading to nephrotic syndrome, hypocomplementemia, hypertension, proteinuria and end-stage kidney disease. MPGN can be due to either idiopathic (type 1, 2 and 3 MPGN) or secondary (associated with infectious and immune complex diseases) causes. Mesangiocapillary glomerulonephritis NCIT:C34644 Orphanet:54370 SCTID:80321008 UMLS:C0017662 membranoproliferative glomerulonephritis