acquired monoclonal Ig light chain-associated Fanconi syndrome Fanconi syndrome (FS) is a generalized disorder of renal proximal tubule function. In adults over 50 years of age, FS is frequently related to the urinary secretion of a monoclonal immunoglobulin (Ig) light chain (LC), almost always of the kappa isotype. ICD10:E72.0 MONDO:0019604 Orphanet:91136 SCTID:724099000 UMLS:C4510369 UMLS:CN206457 acquired Fanconi syndrome secondary to monoclonal gammopathy acquired monoclonal immunoglobulin light chain-associated Fanconi syndrome hematological disorder with renal involvement