Cryoglobulinemic vasculitis type II mixed cryoglobulinemia ICD10:D89.1 MC type II MONDO:0019726 Orphanet:93554 Type II mixed cryoglobulinemia, a relatively rare clinico-serological subtype of mixed cryoglobulinemia (MC), is an immune complex disorder characterized by purpura, weakness and arthralgia and defined immunochemically by cryoglobulins composed of polyclonal IgGs (autoantigens) and monoclonal IgM (autoantibody). UMLS:CN206633