metabolic disease proteostasis deficiencies Disorders caused by imbalances in the protein homeostasis network - synthesis, folding, and transport of proteins; post-translational modifications; and degradation or clearance of misfolded proteins. MESH:D057165 MONDO:0021179 Misfolding disease, Protein Misfolding diseases, Protein Misfolding disorder, Protein Misfolding disorders, Protein Protein Misfolding disease Protein Misfolding diseases Protein Misfolding disorder Protein Misfolding disorders Protein folding disease Protein folding diseases Protein folding disorder Protein folding disorders Proteostasis deficiency Proteostasis dysfunction Proteostasis dysfunctions UMLS:C2718001 deficiencies, Proteostasis deficiency, Proteostasis disease, Protein Misfolding disease, Protein folding diseases, Protein Misfolding diseases, Protein folding disorder, Protein Misfolding disorder, Protein folding disorders, Protein Misfolding disorders, Protein folding dysfunction, Proteostasis dysfunctions, Proteostasis folding disease, Protein folding diseases, Protein folding disorder, Protein folding disorders, Protein proteinopathy proteopathic disease proteopathy