disease or disorder metabolic disease nutritional disorder nutritional or metabolic disease A collective term for nutritional disorders resulting from poor absorption or nutritional imbalance, and metabolic disorders resulting from defects in biosynthesis (ANABOLISM) or breakdown (CATABOLISM) of endogenous substances. Editor note: consider expanding to include endocrine ICD10:E00.E90 MESH:D009750 MONDO:0024297 UMLS:C0028715