disease has location elastic fiber integumentary system disease pseudoxanthoma elasticum (inherited or acquired) An inherited disorder that causes calcium and other minerals to accumulate in the elastic fibers of the skin, eyes, and blood vessels, and less frequently in other areas such as the digestive tract. ICD9:757.39 MONDO:0024308 PXE SCTID:252246005 https://rarediseases.info.nih.gov/diseases/9643/pseudoxanthoma-elasticum pseudoxanthoma elasticum