disease has basis in dysfunction of KYNU congenital vertebral-cardiac-renal anomalies syndrome vertebral, cardiac, renal, and limb defects syndrome 2 MONDO:0060555 OMIM:617661 UMLS:C4540014 VCRL2 congenital NAD deficiency disorder 2 kynureninase deficiency, complete vertebral, cardiac, renal, and limb defects syndrome 2