severity of adverse event AE severity G2 a severity of AE for which only minimal, local, or noninvasive intervention (e.g. packing, cautery) is indicated, or that limits instrumental activities of daily living (ADLs, e.g., shopping, laundry, transportation, or ability to conduct finances). Note the AE severity Grade 2 equals to CTCAE G2 AE severity. Web: http://ncicb.nci.nih.gov/xml/owl/EVS/ctcae.owl#Grade_2_Adverse_Event YH, SS CTCAE4: E10006 (Grade 2 Adverse Event) AE severity Grade 2