part_of part of part of only_in_taxon only in taxon develops_from develops from develops from immediate transformation of Bilateria Homo sapiens Homo sapiens nervous system central nervous system OpenCyc:Mx4rvzYt3pwpEbGdrcN5Y29ycA BILA:0000080 AAO:0000090 CNS EHDAA2:0000225 FMA:55675 EMAPA:16470 BIRNLEX:1099 UBERON:0001017 Wikipedia:Central_nervous_system XAO:0000215 EV:0100163 systema nervosum centrale TAO:0000012 BTO:0000227 ZFA:0000012 UMLS:C0927232 The brain and spinal cord. Kimmel et al, 1995.[TAO] neuronames:854 cerebrospinal axis EHDAA:828 SCTID:278199004 FBbt:00005094 EFO:0000908 MESH:D002490 The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the neural tube derivatives: the brain and spinal cord. In invertebrates it includes central ganglia plus nerve cord. BAMS:CNS CALOHA:TS-0150 uberon VHOG:0000293 MAT:0000457 The central nervous system (CNS) is the part of the nervous system which includes the brain, spinal cord, and nerve cell layer of the retina (CUMBO). EMAPA:16754 GAID:570 neuraxis Part of the nervous system which includes the brain and spinal cord.[AAO] NCIT:C12438 (...) at some stage of its development, every chordate exhibits five uniquely derived characters or synapomorphies of the group: (...) (4) a single, tubular nerve cord that is located dorsal to the notochord (...) (reference 1); The neural tube is destined to differentiate into the brain and spinal cord (the central nervous system) (reference 2); Taken together, our data make a very strong case that the complex molecular mediolateral architecture of the developing trunk CNS (central nervous system), as shared between Platynereis and vertebrates, was already present in their last common ancestor, Urbilateria. The concept of bilaterian nervous system centralization implies that neuron types concentrate on one side of the trunk, as is the case in vertebrates and many invertebrates including Platynereis, where they segregate and become spatially organized (as opposed to a diffuse nerve net). Our data reveal that a large part of the spatial organization of the annelid and vertebrate CNS was already present in their last common ancestor, which implies that Urbilateria had already possessed a CNS (reference 3).[well established][VHOG] MA:0000167 ectoderm-derived structure organ system subdivision future central nervous system