part_of part of part of deep_to superficial_to develops_from develops from develops from composed primarily of material entity material entity mesoderm adipose tissue musculature dermis hypodermis A layer separating the inner face of the dermis from the subjacent muscle cells. It is covered on both sides by a basement membrane. It contains pigment cells. Le Guellec et al, 2004.[TAO] A layer separating the inner face of the dermis from the subjacent muscle cells. It is covered on both sides by a basement membrane. It contains pigment cells[FMA:70544]. BTO has 'subcutis', as part of dermis. We follow FMA in having distinct classes for hypodermis and superficial fascia, and including these as part of the non-skin intgeument. BTO:0001314 CALOHA:TS-2366 FMA:70544 TAO:0001136 UBERON:0002072 UMLS:C0278403 ZFA:0001136 hypodermal subcutaneous subcutaneus uberon vertebrate hypodermis subcutis superficial fascia subcutaneous tissue Lowermost layer of the integumentary system in vertebrates. Types of cells that are found in the hypodermis are fibroblasts, adipose cells, and macrophages. It is derived from the mesoderm, but unlike the dermis, it is not derived from the dermatome region of the mesoderm. The hypodermis is used mainly for fat storage[WP]. sub-tegumental tissue tela subcutanea hypoderm subtegumental tissue integument mesoderm-derived structure loose connective tissue integumentary system layer