antimyasthenic agent therapy parasympathomimetic therapy 2019-01-22T18:47:49Z Treatment with a drug to activate the parasympathetic nervous system (PSNS). They can act as direct agonists of acetylcholine receptors (ACh) or indirect agonists of ACh. While direct agonists act by binding directly to muscarinic or nicotinic ACh receptors, indirect agonists prolong the action of endogenous acetylcholine by inhibiting acetylcholinesterase. cholinomimetic medication therapy parasympathomimetic drug therapy treatment with parasympathomimetic drug treatment with parasympathomimetic medication Direct agonists of ACh are used topically in ophthalmology to induce miosis, while indirect agonists are used to treat, e.g., postoperative ileus or urinary retention and myasthenia gravis. parasympathomimetic agent therapy treatment with cholinomimetic drug cholinomimetic drug therapy treatment with parasympathomimetic agent cholinomimetic agents therapy parasympathomimetic medication therapy treatment with cholinomimetic agent treatment with cholinomimetic medication parasympathomimetic drug treatment