<?xml version="1.0"?>
<?xml-stylesheet type="text/xsl" href="https://ontobee.org/ontology/view/MAXO?iri=http://purl.obolibrary.org/obo/MAXO_0000434"?>
<rdf:RDF xmlns="http://www.w3.org/2002/07/owl#"
     xml:base="http://www.w3.org/2002/07/owl"
     xmlns:rdf="http://www.w3.org/1999/02/22-rdf-syntax-ns#"
     xmlns:owl="http://www.w3.org/2002/07/owl#"
     xmlns:oboInOwl="http://www.geneontology.org/formats/oboInOwl#"
     xmlns:xsd="http://www.w3.org/2001/XMLSchema#"
     xmlns:dcterms="http://purl.org/dc/terms/"
     xmlns:rdfs="http://www.w3.org/2000/01/rdf-schema#"
     xmlns:ns4="http://purl.obolibrary.org/obo/"
     xmlns:foaf="http://xmlns.com/foaf/0.1/"
     xmlns:dc="http://purl.org/dc/elements/1.1/">
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Annotation properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
    <AnnotationProperty rdf:about="http://purl.org/dc/terms/creator"/>
    <AnnotationProperty rdf:about="http://purl.obolibrary.org/obo/IAO_0000115"/>
    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasDbXref"/>
    <AnnotationProperty rdf:about="http://purl.org/dc/elements/1.1/date"/>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Datatypes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Object Properties
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/MAXO_0000864 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/MAXO_0000864">
        <rdfs:label xml:lang="en">therapeutic uses</rdfs:label>
    </ObjectProperty>
    


    <!-- http://purl.obolibrary.org/obo/RO_0000087 -->

    <ObjectProperty rdf:about="http://purl.obolibrary.org/obo/RO_0000087">
        <rdfs:label xml:lang="en">has role</rdfs:label>
    </ObjectProperty>
    


    <!-- 
    ///////////////////////////////////////////////////////////////////////////////////////
    //
    // Classes
    //
    ///////////////////////////////////////////////////////////////////////////////////////
     -->

    


    <!-- http://purl.obolibrary.org/obo/CHEBI_24431 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_24431">
        <rdfs:label>chemical entity</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_38215 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_38215">
        <rdfs:label>calcium channel blocker</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MAXO_0000058 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MAXO_0000058">
        <rdfs:label>pharmacotherapy</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MAXO_0000161 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MAXO_0000161">
        <rdfs:label>receptor antagonist therapy</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MAXO_0000205 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MAXO_0000205">
        <rdfs:label>calcium channel modifying agent therapy</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/MAXO_0000434 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/MAXO_0000434">
        <rdfs:label>calcium channel blocking agent therapy</rdfs:label>
        <equivalentClass>
            <Class>
                <intersectionOf rdf:parseType="Collection">
                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/MAXO_0000058"/>
                    <Restriction>
                        <onProperty rdf:resource="http://purl.obolibrary.org/obo/MAXO_0000864"/>
                        <someValuesFrom>
                            <Class>
                                <intersectionOf rdf:parseType="Collection">
                                    <rdf:Description rdf:about="http://purl.obolibrary.org/obo/CHEBI_24431"/>
                                    <Restriction>
                                        <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                                        <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_38215"/>
                                    </Restriction>
                                </intersectionOf>
                            </Class>
                        </someValuesFrom>
                    </Restriction>
                </intersectionOf>
            </Class>
        </equivalentClass>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MAXO_0000161"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/MAXO_0000205"/>
        <rdfs:subClassOf>
            <Restriction>
                <onProperty rdf:resource="http://purl.obolibrary.org/obo/MAXO_0000864"/>
                <someValuesFrom>
                    <Class>
                        <intersectionOf rdf:parseType="Collection">
                            <rdf:Description rdf:about="http://purl.obolibrary.org/obo/CHEBI_24431"/>
                            <Restriction>
                                <onProperty rdf:resource="http://purl.obolibrary.org/obo/RO_0000087"/>
                                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_38215"/>
                            </Restriction>
                        </intersectionOf>
                    </Class>
                </someValuesFrom>
            </Restriction>
        </rdfs:subClassOf>
        <dc:date rdf:datatype="http://www.w3.org/2001/XMLSchema#dateTime">2019-09-27T19:41:29Z</dc:date>
        <oboInOwl:hasDbXref>NCIT:C333</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>calcium channel antagonist therapy</oboInOwl:hasExactSynonym>
        <rdfs:comment>One of a class of drugs that acts by selective inhibition of calcium influx through cell membranes or on the release and binding of calcium in intracellular pools.</rdfs:comment>
        <oboInOwl:hasExactSynonym>treatment with calcium channel blocker drug</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>treatment with calcium channel blocker</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>treatment with calcium channel blocking drug</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>treatment with calcium channel blocking medication</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>Ca2+ channel blocker therapy</oboInOwl:hasExactSynonym>
        <ns4:IAO_0000115>Treatment with a pharmaceutical agent that inhibits the movement of calcium across through calcium channels in the cell membrane, preventing or decreasing the amount of calcium able to enter the cell. These drugs are used for their chronotropic, antihypertensive and vasodilatory effects.</ns4:IAO_0000115>
        <oboInOwl:hasExactSynonym>treatment with calcium channel blocker medication</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>calcium channel blocker drug therapy</oboInOwl:hasExactSynonym>
        <oboInOwl:hasExactSynonym>calcium channel antagonist drug therapy</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref>CHEBI:38215</oboInOwl:hasDbXref>
        <oboInOwl:hasExactSynonym>Ca2+ channel antagonist therapy</oboInOwl:hasExactSynonym>
        <dcterms:creator rdf:resource="http://orcid.org/0000-0001-7941-2961"/>
    </Class>
</rdf:RDF>



<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



