part of develops from composed primarily of existence starts during migratory neural crest cell neurula stage neural crest VHOG:0000057 NCIT:C34222 BTO:0001764 neuronames:1366 EHDAA2:0004419 NC SCTID:361462002 CALOHA:TS-0676 neural crest material EMAPA:32737 ZFA:0000045 crista neuralis Wikipedia:Neural_crest A specialized region of ectoderm found between the neural ectoderm (neural plate) and non-neural ectoderm and composed of highly migratory pluripotent cells that delaminate in early embryonic development from the dorsal neural tube and give rise to an astounding variety of differentiated cell types[MP]. XAO:0000048 AAO:0010578 Gene notes: Many factors and genes, such as Pax3 (Tremblay et al., 1995), slug (Nieto et al., 1994), AP-2 (Zhang et al., 1996; Schorle et al., 1996), and Wnt-1/3a (Ikeya et al., 1997) are expressed in the dorsal most region of the neural tube, and have been shown to be involved in the generation of neural crest cells. MIAA:0000066 MAT:0000066 FMA:86666 MESH:D009432 GAID:1310 neurectoderm neural plate ectoderm-derived structure neural fold germ layer / neural crest