dyslipidemic agent therapy bile acid sequestrant therapy 2020-11-17T21:21:54Z bile-acid sequestrant agent therapy treatment with bile-acid sequestrant bile-acid sequestrant therapy Therapy using a highly charged polymeric agent to bind bile acids in the gastrointestinal tract and prevent their reabsorption from the gut. The bound bile acids are excreted with the feces and plasma cholesterol is converted to bile acid to reestablish normal bile acid levels, resulting in a lowering of plasma cholesterol concentrations.