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    <AnnotationProperty rdf:about="http://www.geneontology.org/formats/oboInOwl#hasExactSynonym"/>
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    <!-- http://purl.obolibrary.org/obo/CHEBI_17650 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_17650">
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">cortisol</rdfs:label>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_24261"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35342"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35344"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35346"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_36885"/>
        <rdfs:subClassOf rdf:resource="http://purl.obolibrary.org/obo/CHEBI_47909"/>
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                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_77746"/>
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                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_35472"/>
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                <someValuesFrom rdf:resource="http://purl.obolibrary.org/obo/CHEBI_75771"/>
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        <oboInOwl:hasRelatedSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">(11beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">0</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasExactSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">11beta,17,21-trihydroxypregn-4-ene-3,20-dione</oboInOwl:hasExactSynonym>
        <oboInOwl:hasRelatedSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">11beta,17alpha,21-trihydroxy-4-pregnene-3,20-dione</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">11beta-hydrocortisone</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">17-hydroxycorticosterone</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">362.209</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">362.45990</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">4-pregnen-11beta,17alpha,21-triol-3,20-dione</oboInOwl:hasRelatedSynonym>
        <ns4:IAO_0000115 rdf:datatype="http://www.w3.org/2001/XMLSchema#string">A C21-steroid that is pregn-4-ene substituted by oxo groups at positions 3 and 20 and hydroxy groups at positions 11, 17 and 21. Cortisol is a corticosteroid hormone or glucocorticoid produced by zona fasciculata of the adrenal cortex, which is a part of the adrenal gland. It is usually referred to as the &quot;stress hormone&quot; as it is involved in response to stress and anxiety, controlled by corticotropin-releasing hormone (CRH). It increases blood pressure and blood sugar, and reduces immune responses</ns4:IAO_0000115>
        <oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Beilstein:1354819</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">C21H30O5</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CAS:50-23-7</oboInOwl:hasDbXref>
        <oboInOwl:hasAlternativeId rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CHEBI:14023</oboInOwl:hasAlternativeId>
        <oboInOwl:id rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CHEBI:17650</oboInOwl:id>
        <oboInOwl:hasAlternativeId rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CHEBI:24633</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CHEBI:3893</oboInOwl:hasAlternativeId>
        <oboInOwl:hasAlternativeId rdf:datatype="http://www.w3.org/2001/XMLSchema#string">CHEBI:58221</oboInOwl:hasAlternativeId>
        <oboInOwl:hasExactSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Cortisol</oboInOwl:hasExactSynonym>
        <oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">DrugBank:DB00741</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Drug_Central:1388</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Hydrocortisone</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">InChI=1S/C21H30O5/c1-19-7-5-13(23)9-12(19)3-4-14-15-6-8-21(26,17(25)11-22)20(15,2)10-16(24)18(14)19/h9,14-16,18,22,24,26H,3-8,10-11H2,1-2H3/t14-,15-,16-,18+,19-,20-,21-/m0/s1</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">JYGXADMDTFJGBT-VWUMJDOOSA-N</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">KEGG:C00735</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">KEGG:D00088</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Kendall&#39;s compound F</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">LINCS:LSM-5980</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">LIPID_MAPS_instance:LMST02030001</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PDBeChem:HCY</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:10438974</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">PMID:2268561</oboInOwl:hasDbXref>
        <oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Patent:US2602769</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Reichstein&#39;s substance M</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref rdf:datatype="http://www.w3.org/2001/XMLSchema#string">Wikipedia:Hydrocortisone</oboInOwl:hasDbXref>
        <oboInOwl:hasRelatedSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">[H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])[C@@H](O)C[C@@]1(C)[C@@]2([H])CC[C@]1(O)C(=O)CO</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasOBONamespace rdf:datatype="http://www.w3.org/2001/XMLSchema#string">chebi_ontology</oboInOwl:hasOBONamespace>
        <oboInOwl:hasExactSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">cortisol</oboInOwl:hasExactSynonym>
        <oboInOwl:hasRelatedSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">hidrocortisona</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">hydrocortisone</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasRelatedSynonym rdf:datatype="http://www.w3.org/2001/XMLSchema#string">hydrocortisonum</oboInOwl:hasRelatedSynonym>
        <oboInOwl:hasDbXref>colombos:HYDROCORTISONE</oboInOwl:hasDbXref>
        <oboInOwl:inSubset rdf:resource="http://purl.obolibrary.org/obo/chebi#3_STAR"/>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_24261 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_24261">
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">glucocorticoid</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_35342 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_35342">
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">17alpha-hydroxy steroid</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_35344 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_35344">
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">21-hydroxy steroid</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_35346 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_35346">
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">11beta-hydroxy steroid</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_35472 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_35472">
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">anti-inflammatory drug</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_36885 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_36885">
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">20-oxo steroid</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_47909 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_47909">
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">3-oxo-Delta(4) steroid</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_49167 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_49167">
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">anti-asthmatic drug</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_50857 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_50857">
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">anti-allergic agent</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_61313 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_61313">
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">C21-steroid</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_75771 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_75771">
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">mouse metabolite</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_77746 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_77746">
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">human metabolite</rdfs:label>
    </Class>
    


    <!-- http://purl.obolibrary.org/obo/CHEBI_8386 -->

    <Class rdf:about="http://purl.obolibrary.org/obo/CHEBI_8386">
        <rdfs:label rdf:datatype="http://www.w3.org/2001/XMLSchema#string">pregnane</rdfs:label>
    </Class>
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<!-- Generated by the OWL API (version 3.2.4.1806) http://owlapi.sourceforge.net -->



