has role antimetabolite antineoplastic agent hydroxyurea 0 76.027 76.05474 A member of the class of ureas that is urea in which one of the hydrogens is replaced by a hydroxy group. An antineoplastic used in the treatment of chronic myeloid leukaemia as well as for sickle-cell disease. Beilstein:1741548 CAS:127-07-1 CH4N2O2 CHEBI:44420 CHEBI:44423 CHEBI:5816 DrugBank:DB01005 Drug_Central:1399 Gmelin:130423 HMDB:HMDB15140 Hydroxycarbamid Hydroxycarbamide Hydroxyharnstoff Hydroxyurea InChI=1S/CH4N2O2/c2-1(4)3-5/h5H,(H3,2,3,4) KEGG:C07044 KEGG:D00341 MetaCyc:HYDROXY-UREA N-HYDROXYUREA N-carbamoylhydroxylamine N-hydroxyurea NC(=O)NO PDBeChem:NHY PMID:11285159 PMID:11298103 PMID:11364534 PMID:11365149 PMID:11391710 PMID:12107454 PMID:14988684 PMID:15772364 PMID:15994344 PMID:16356682 PMID:22983419 PMID:23318979 PMID:23643402 PMID:23696560 PMID:9271088 Patent:US2705727 Reaxys:1741548 VSNHCAURESNICA-UHFFFAOYSA-N Wikipedia:Hydroxyurea carbamohydroxamic acid carbamohydroximic acid carbamoyl oxime carbamyl hydroxamate chebi_ontology hidroxicarbamida hydrea hydroxycarbamide hydroxycarbamidum hydroxyurea oxyurea ureas radical scavenger immunomodulator genotoxin teratogenic agent DNA synthesis inhibitor one-carbon compound antimitotic EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor