schizotypal personality disorder A personality disorder that involves a need for social isolation, anxiety in social situations, odd behavior and thinking, and often unconventional beliefs. DOID:10646 ICD9CM:301.22 MSH:D012569 SNOMEDCT_2010_1_31:231486008 SNOMEDCT_2010_1_31:31027006 UMLS_CUI:C0036363 disease_ontology MFOMD_0000044 301.22 Personality disorder that is a pattern of acute discomfort in close relationships, cognitive or perceptual distortions, and eccentricities of behaviour. DSM-IV-TR (american Psychiatric Association) People with this personality disorder manifest peculiar thoughts and behaviours and have poor interpersonal relationships. Many believe they posses magical thinking abilities or special powers, and some are subject to recurrent illusions. Speech oddities, such as frequent digression or vagueness in conversation, are often present. The evaluation of individuals must take into account their cultural milieu. The people with this disorder seem to have problems in thinking and perceiving; and often show social isolation, hypersensitivity, and inappropriate affect (emotions); they seem to lack pleasure from social interactions. Research has demonstrated some cognitive processing abnormalities in individuals with schizotypal personality disorder that help to explain many of the symptoms, and is more prevalent among the first-degree biological relatives of individuals with Schizophrenia than the general population. "Understanding abnormal behavior". David Sue, Derald Wing Sue, Stanley Sue. DSM-IV-TR (american Psychiatric Association) F21 Trastorno esquizotípico de la personalidad personality disorder