major depressive disorder An endogenous depression that is characterized by an all-encompassing low mood accompanied by low self-esteem, and by loss of interest or pleasure in normally enjoyable activities. DOID:10614 DOID:1470 DOID:2240 DOID:2241 DOID:7580 ICD10CM:F32 ICD10CM:F33 ICD9CM:296 ICD9CM:296.20 ICD9CM:296.3 ICD9CM:296.30 NCI:C34796 OMIM:608520 OMIM:608691 SNOMEDCT_2010_1_31:191599006 SNOMEDCT_2010_1_31:191600009 SNOMEDCT_2010_1_31:191607007 SNOMEDCT_2010_1_31:191608002 SNOMEDCT_2010_1_31:191609005 SNOMEDCT_2010_1_31:191617002 SNOMEDCT_2010_1_31:192366006 SNOMEDCT_2010_1_31:268620009 SNOMEDCT_2010_1_31:268621008 SNOMEDCT_2010_1_31:36923009 SNOMEDCT_2010_1_31:66344007 UMLS_CUI:C0024517 UMLS_CUI:C0154409 Xref MGI. disease_ontology recurrent major depression single major depressive episode The essential feature is a clinical course that is characterised by one or more Major Depressive Episodes without a history of Manic, Mixed, or Hypomanic episodes. Symptoms of Depression Affective domain.- Sadness, unhappiness, apathy, anxiety, brooding Cognitive domain.- Pessimism, guilt, inability to concentrate, negative thinking, loss of interest and motivation, suicidal thoughts. Behavioural domain.- Low energy, neglect of personal appearance, crying, psychomotor retardation, agitation. Physiological domain.- Poor or increased appetite, constipation, sleep disturbance, disruption of the menstrual cycle in women, loss of sex drive. "Understanding abnormal behavior". David Sue, Derald Wing Sue, Stanley Sue. MFOMD_0000144 MFOMD_0000049 depressive disorder major depressive disorder [DSM-IV] DSM-IV lists several codes for depression depending on the most recent episode: 296.36 Major Depressive Disorder, Recurrent, In Full Remission 296.35 Major Depressive Disorder, Recurrent, In Partial Remission 296.31 Major Depressive Disorder, Recurrent, Mild 296.32 Major Depressive Disorder, Recurrent, Moderate 296.34 Major Depressive Disorder, Recurrent, Severe With Psychotic Features 296.33 Major Depressive Disorder, Recurrent, Severe Without Psychotic Features 296.3 Major Depressive Disorder, Recurrent, Unspecified 296.26 Major Depressive Disorder, Single Episode, In Full Remission 296.25 Major Depressive Disorder, Single Episode, In Partial Remission 296.21 Major Depressive Disorder, Single Episode, Mild 296.22 Major Depressive Disorder, Single Episode, Moderate 296.24 Major Depressive Disorder, Single Episode, Severe With Psychotic Features 296.23 Major Depressive Disorder, Single Episode, Severe Without Psychotic Features 296.2 Major Depressive Disorder, Single Episode, Unspecified depression endogenous depression