personality disorder A disease of mental health that involve long-term patterns of thoughts and behaviors that cause serious problems with relationships and work. DOID:1510 ICD9CM:301.8 ICD9CM:301.89 SNOMEDCT_2010_1_31:191770003 SNOMEDCT_2010_1_31:191776009 SNOMEDCT_2010_1_31:268635005 SNOMEDCT_2010_1_31:268759009 UMLS_CUI:C0029707 character disorder disease_ontology MFOMD_0000039 Only when personality traits are inflexible and maladaptive and cause significant functional impairment or subjective distress do they constitute Personality Disorders. DSM-IV-TR (american Psychiatric Association) Personality disorder is an enduring pattern of inner experience and behaviour that deviates markedly from the expectations of the individual's culture, is pervasive and inflexible, has an onset in adolescence or early adulthood, is stable over the time, and leads to distress or impairment. DSM-IV-TR trastornos de la personalidad mental disorder