sequence based phylogenetic profile sequence based prediction of gene regulatory region binding sites phylogenetic profiling of predicted gene regulatory region binding sites PSI-MI 2012-06-07T01:41:59Z Sequence analysis based on multiple homologous alignments of the regulatory region of a gene used to predict specific elements, transcription factor binding sites (TFBS), where binding of specific transcription factors can occur. These methods often also use transcription factor binding motif models. MI:1177 orchard phylogenetic footprinting gene regulatory region phylogeny