has role triol buffer primary amino compound tris 1,1,1-tris(hydroxymethyl)methanamine 121.074 121.13500 2-Amino-2-(hydroxymethyl)-1,3-propanediol 2-amino-2-(hydroxymethyl)propane-1,3-diol A primary amino compound that is tert-butylamine in which one hydrogen attached to each methyl group is replaced by a hydroxy group. A compound widely used as a biological buffer substance in the pH range 7--9; pKa = 8.3 at 20 degreeC; pKa = 7.82 at 37 degreeC. Beilstein:741883 C4H11NO3 CAS:77-86-1 CHEBI:9754 DrugBank:DB03754 Drug_Central:2771 Gmelin:217857 InChI=1S/C4H11NO3/c5-4(1-6,2-7)3-8/h6-8H,1-3,5H2 KEGG:C07182 KEGG:D00396 LENZDBCJOHFCAS-UHFFFAOYSA-N NC(CO)(CO)CO PDBeChem:TRS PMID:22553829 Reaxys:741883 THAM Tris Tris amino Tris base Tris buffer Tris-base Trizma Trometamol Tromethamine Wikipedia:Tris aminotris(hydroxymethyl)methane chebi_ontology tris(hydroxymethyl)aminomethane