has_material_basis_in systemic mycosis invasive aspergillosis An aspergillosis that is characterized by the presence of septate, acute, branching hyphae invading lung tissue. [ NCI ] Occurs when Aspergillus causes a serious infection, and usually affects people who have weakened immune systems, such as people who have had an organ transplant or a stem cell transplant. Invasive aspergillosis most commonly affects the lungs, but it can also spread to other parts of the body. http://purl.obolibrary.org/obo/NCIT aspergillosis