metabolic resistance carboxylesterase resistance COE resistance MIRO:00000012 MIRO:00000012 Metabolic resistance due to qualitative or quantitative changes in COE gene products (group of hydrolase enzymes capable of hydrolyzing compounds containing ester bonds) resulting in more efficient insecticide sequestration or metabolism. PMID:16925478 mosquito_insecticide_resistance_ontology metabolic resistance carboxylesterase resistance COE resistance MIRO:00000012 MIRO:00000012 Metabolic resistance due to qualitative or quantitative changes in COE gene products (group of hydrolase enzymes capable of hydrolyzing compounds containing ester bonds) resulting in more efficient insecticide sequestration or metabolism. PMID:16925478 mosquito_insecticide_resistance_ontology