cysTMT6plex reporter+balance reagent cysteine disulfide cysTMT6plex-zero reporter+balance reagent cysteine disulfide (12)C 14 H 25 (14)N 3 O 2 S 1 (12)C 17 H 32 (14)N 4 O 4 S 2 299.166748046875 299.170013427734375 420.186492919921875 420.19000244140625 A protein modification that effectively replaces a residue sulfhydryl hydrogen with a Thermo Scientific cysTMT6plex-zero reporter+balance group. C MOD:01822 Native cysteine-reactive Tandem Mass Tag(TM) PSI-MOD S-(2-{3-[2-(2,6-dimethylpiperidin-1-yl)acetamido]propanamido}ethyl)sulfanyl The reagent consists of a reporter group, a balance group and a protein sulfhydryl reactive pyridine disulfanyl group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification. Unimod:984 artifact cysTMT