cysTMT6plex reporter+balance reagent cysteine disulfide cysTMT6plex-127 reporter+balance reagent cysteine disulfide 304.177215576171875 304.290008544921875 425.19696044921875 425.410003662109375 The reagent consists of a reporter group, a balance group and a protein sulfhydryl reactive pyridine disulfanyl group. The reporter group, an isotopically labeled 1,2,6-trimethylpiperidine, is connected to a 3-(carbonylamino)propanoyl balance group that is isotopically labeled to produce a nominally isobaric combined modification. PSI-MOD H 32 (12)C 13 (13)C 4 (14)N 3 (15)N 1 O 4 S 2 C A protein modification that effectively replaces a residue sulfhydryl hydrogen with a Thermo Scientific cysTMT6plex-127 reporter+balance group. artifact H 25 (12)C 10 (13)C 4 (14)N 2 (15)N 1 O 2 S 1 cysTMT6plex cysteine-reactive Sixplex Tandem Mass Tag(TM) none MOD:01824 S-(2-{3-[2-(2,6-dimethylpiperidin-1-yl)acetamido]propanamido}ethyl)sulfanyl