obsolete monogenic disease https://github.com/monarch-initiative/mondo/issues/1758 true MONDO:0000275 DOID:0050177 OBSOLETE. A genetic disease that is the result of one or more abnormal alleles and may be dominant (a single copy of the abnormal allele is sufficient to give rise to the disease), semi-dominant, or recessive (requiring both copies of the gene to have an abnormal allele). hereditary disease