disease has location disease_has_basis_in_development_of disease has major feature Orofacial cleft orofacial cleft https://www.malacards.org/card/orofacial_cleft MONDO:0000358 UMLS:C3266076 OMIMPS:119530 DOID:0050567 A disorder of facial skeleton that is characterized by cleft lip and/or cleft palate that result in feeding, speech and hearing problems caused by failures during development. SCTID:449790007 Editor notes: most subtypes are isolated MEDGEN:472000 hereditary disease disorder of facial skeleton face embryonic facial prominence