primary progressive multiple sclerosis https://www.malacards.org/card/primary_progressive_multiple_sclerosis UMLS:C0751964 EFO:0008520 SCTID:428700003 icd11.foundation:1020720762 NANDO:2201320 MONDO:0000451 MEDGEN:155968 DOID:0050784 NANDO:1200025 A multiple sclerosis that is characterized by steady worsening of neurologic functioning, without any distinct relapses or periods of remission. The rate of progression may vary over time, with occasional plateaus or temporary improvements, but the progression is continuous. chronic progressive multiple sclerosis