cerebral cavernous malformation https://www.malacards.org/card/cerebral_cavernous_malformations UMLS:C2919945 icd11.foundation:916773262 CCM cerebral cavernous malformation MONDO:0000820 MEDGEN:418825 DOID:0060669 brain cavernous hemangioma A disorder characterized by malformations in the structure of the capillaries in the brain. It is caused by mutations in the CCM2, KRIT1 and PDCD10 genes. The capillaries fill with blood and stretch, thereby creating cavernous spaces. Some patients experience headaches, seizures, or visual and hearing disturbances. Cerebral hemorrhage may also occur. NCIT:C84626 Orphanet:164 congenital nervous system disorder central nervous system hemangioma