disease has basis in disruption of disease caused by disruption of disease arises from feature disease has basis in feature disease has feature epithelial structure maintenance Reduced circulating vitamin A concentration Corneal opacity keratomalacia https://github.com/monarch-initiative/mondo/issues/9097 https://www.malacards.org/card/keratomalacia icd11.foundation:497316188 DOID:11267 An eye disorder that results from vitamin A deficiency, with basis in disruption of maintenance of the specialized epithelial surfaces, leading to atrophic changes in the normal mucosal surface, with loss of goblet cells, and replacement of the normal epithelium by an inappropriate keratinized stratified squamous epithelium. In addition, the substantia propria of the cornea breaks down and liquefies, resulting in keratomalacia. UMLS:C0152455 MESH:C536156 MEDGEN:57777 MONDO:0001250 ICD9:371.45 SCTID:85149007 ICD10CM:H18.44 corneal degeneration eye disorder