disease has feature orthostatic intolerance https://github.com/monarch-initiative/mondo/issues/10150 https://www.malacards.org/card/orthostatic_intolerance MONDO:0001315 neurocirculatory asthenia DOID:11569 postural orthostatic tachycardia syndrome A chronic disorder of dysautonomia, characterized by palpitation, shortness of breath, labored breathing, and subjective complaints of effort and discomfort provoked by physical exertion or upright posture, often accompanied by dizziness, tremulousness, sweating, and insomnia. The heart rate increases by at least 30 beats per minute when moving from a recumbent to a standing position (or ≥40 bpm in individuals 12-19 years of age), without orthostatic hypotension. Historically described as soldier's heart, irritable heart, effort syndrome, or Da Costa syndrome. Anxiety is a frequently associated feature rather than the underlying cause. irritable heart MEDGEN:283928 ICD9:306.2 soldiers heart POTS postural tachycardia syndrome cardiovascular malfunction arising from mental factors MESH:D009449 SCTID:191962000 UMLS:C1535893 somatoform disorder anxiety disorder anxiety dysautonomia